Mouse insulin and glucose studies can be conducted safely and efficiently with the right high-quality supplies from SAI.
Insulin sensitivity studies can become complex and challenging, but we are here to provide the support and resources you need for success. Whether your research involves Glucose Tolerance Tests (GTT), Hyperglycemic Clamp techniques, or Hyperinsulinemic-Euglycemic Clamp protocols, we offer expert guidance and tailored recommendations to streamline your process. Explore our curated selection of supplies and solutions below to ensure your studies are conducted with precision, reliability, and ease.
Supplies for ITT and GTT Studies
In this study design, a loading dose of glucose (gtt) or insulin (itt) is followed by intermittent blood sampling. The dose is typically administered orally, and since multiple blood samples are needed, an access port is the best tool to make catheter access quick and easy.
Mouse Jugular Catheter
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Rodent Disposable Feeding Needles
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CannuLock™ Catheter Access Ports, Sterile
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Supplies for Hyperglycemic Clamp Studies
In this study design, glucose is infused intravenously with adjustments to reach a steady state. From there, intermittent blood samples are collected and analyzed to establish glucose levels. Since the mouse must be tethered, and low-stress, the CannuLock™ Catheter Access Button™ is an ideal tool.
Mouse Jugular Catheter
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This product has multiple variants. The options may be chosen on the product page
Mouse Arterial Catheters without Stylet
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Bile collection 25G swivel to tube extension lines 3/pk
Supplies for Hyperinsulinemic-Euglycemic Clamp Studies
This protocol relies on intravenous (IV) infusion of insulin to set a baseline, as well as variable rate infusion of glucose (into the same IV line). It’s also common to incorporate an additional channel to dose an experimental compound. Intermittent blood sampling for glucose levels will determine the impact of the drug administration on the mouse.
Mouse Jugular Catheter
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This product has multiple variants. The options may be chosen on the product page
Mouse Arterial Catheters without Stylet
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This product has multiple variants. The options may be chosen on the product page
Bile collection 25G swivel to tube extension lines 3/pk